Perfect Solution to Bone Health for Your Pet
Sonadil®
All natural plant based anti-inflammatiory agent, that works well in easing pain fast and safe for long term intake. Sonadil® is made from a patented ingredient - Aflapin®, a novel synergistic composition derived from Boswellia serrata gum resin (Patent Application No. 2229/CHE/2008). Sonadil® is significantly better as an anti-inflammatory agent. Corroborating the improvements in pain scores in treatment groups, our in vitro studies provide evidences that Sonadil® is capable of inhibiting cartilage degrading enzyme MMP-3 and has the potential to regulate the inflammatory response by inhibiting ICAM-1. Sonadil® reduces pain and improve physical functions significantly in OA and bone-fractured subjects.
Indication & Recommended Use
Traditionally used for reducing pain, natural anti inflammatory agent.
Dosage & Ingredients
One capsule after food daily for animal below 20kg.
Two capsules after food daily for pets weighing 21-40kg.
Packaging & Where To Buy
1 box x 3 strip x 10 capsules
Available at selected VETERINARY CLINICS throughout South East Asia.
Safety and toxicology tested.
To assess the safety of Sonadil®, a battery of acute and sub-acute toxicity studies were conducted in various animal models according to the OECD test guidelines. The acute oral LD50 of Aflapin was greater than 5000 mg/kg in female Sprague Dawley (SD) rats. Acute dermal LD50 of Sonadil® - in was greater than 2000 mg/kg in SD rats. A primary dermal irritation study conducted using New Zealand White rabbits indicated that Sonadil® is non-irritating to skin. A repeat dose 28-day sub-acute oral toxicity study in SD rats demonstrated no significant signs of toxicity. Various evaluations including hematology, clinical chemistry, gross necropsy, and histopathology did not show any significant adverse changes. The NOAEL of Sonadil® was found to be greater than 2500 mg/kg body weight. These studies demonstrate broad spectrum safety of Sonadil® in animal models.
Indication & Recommended Use
The Major application of Sonadil®
- Joint pain
- Fractured bone - anti inflammation
- Post surgery
- Cancer patient
- Fever
Safety and Toxicological Evaluation of AlgaeCal, A Novel Plant-based Calcium
In preparation for GRAS (Generally Recognized as Safe) status which AlgaeCal® achieved in May 2010, an excellent safety profile was established through testing. Six different safety studies have been conducted on AlgaeCal in the United States and Europe and combined into one manuscript which has been published in the peer-reviewed journal, Toxicology Mechanisms and Actions. These studies include one which tested the toxicity of AlgaeCal® on pregnant and nursing female rats.